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Added by Christian Veillette , last edited by Christian Veillette on Sep 06, 2008  (view change)
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Location Spine
Diagnosis Sickle cell anemia
Discussion Lateral radiographs of the spine reveals central endplate depression with sparing of the anterior and posterior margins of the endplate. Several current names have been ascribed to these same changes seen in patients with hemoglobinopathy, such as Lincoln Log Sign, or H-shaped vertebra. Although not pathognomonic, these terms are typically reserved for a patient with Sickle-Cell disease.
Reference Hansen GC, Gold RH: Central depression of multiple vertebral end-plates: a "pathognomonic" sign of sickle hemoglobinopathy in Gaucher's disease AJR Am J Roentgenol 1977 Aug;129(2):343-4.
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